Hmmmm interesting. Funny you mention it because I was taking gaba not too long ago and it was in a mixture with some other stuff. Anyways, I think it was causing me to wake up kind of uncoordinated and feeling just kind of weird. Dissociative I guess you could say, which makes sense because it’s related to the NMDA receptors somehow I think. It supposedly “can’t” cross the blood brain barrier, at least this is repeated despite the fact that it can and does, it’s just an unreliable mechanism in which it does. Low levels of gaba were insinuated to absorb more in the brain also. I didn’t have this issue as if I took the full 750 mg I felt very strange consistently and none of the other supplements in the mixture would seem to do this.
This is my 2nd time ordering these pills. I took them 2yrs ago and dropped 20lbs. I have about 10lbs I'm trying to get rid of that is being stubborn so I knew immediately I was ordering these again. I am 32 and at this point anything unhealthy that I eat sticks to me like glue. These pills are NO JOKE. My advice is if you have never taken these before take just 1 pill in the morning with breakfast and do NOT drink extra caffeine. It will make you all shakey and possibly sick. Build up a tolerance as you go and drink a lot of water throughout the day. If you do this, eat healthy and exercise 30 mins a day you will drop weight like crazy. Remember though don't take two in the morning and one 4 hours later or you will be sick as a dog and think your heart will explode. They uplift your mood and get the job done. I will never try any other diet pill. Thank you high tech pharmaceuticals for making a pill that works! (Posted on 7/16/2016)
As of May 2016 [update] , the signaling cascade that mediates the HMB-induced reduction in muscle protein breakdown has not been identified in living humans, although it is well-established that it attenuates proteolysis in humans in vivo .   Unlike L -leucine , HMB attenuates muscle protein breakdown in an insulin -independent manner in humans. [note 7]  HMB is believed to reduce muscle protein breakdown in humans by inhibiting the 19S and 20S subunits of the ubiquitin–proteasome system in skeletal muscle and by inhibiting apoptosis of skeletal muscle nuclei via unidentified mechanisms.