Newer medications help reduce the time it takes to fall asleep. Some of these sleep-inducing drugs, which bind to the same receptors in the brain as do benzodiazepines, include Lunesta , Sonata , and Ambien . They are somewhat less likely than benzodiazepines to be habit-forming, but over time can still sometimes cause physical dependence. They can work quickly to increase drowsiness and sleep. Another sleep aid, called Rozerem , acts differently from other sleep medicines by affecting a brain hormone called melatonin, and is not habit-forming. Belsomra is another unique sleep aid that affects a brain chemical called orexin , and is not addictive or habit-forming.
The areas of the brain where cannabinoid receptors are most prevalently located are consistent with the behavioral effects produced by cannabinoids. Brain regions in which cannabinoid receptors are very abundant are the basal ganglia , associated with movement control; the cerebellum , associated with body movement coordination; the hippocampus , associated with learning , memory, and stress control; the cerebral cortex , associated with higher cognitive functions; and the nucleus accumbens , regarded as the reward center of the brain. Other regions where cannabinoid receptors are moderately concentrated are the hypothalamus , which regulates homeostatic functions; the amygdala , associated with emotional responses and fears ; the spinal cord , associated with peripheral sensations like pain; the brain stem , associated with sleep , arousal , and motor control; and the nucleus of the solitary tract , associated with visceral sensations like nausea and vomiting . 
In addition to the mentioned side effects several others have been reported. In both males and females acne are frequently reported, as well as hypertrophy of sebaceous glands, increased tallow excretion, hair loss, and alopecia. There is some evidence that anabolic steroid abuse may affect the immune system, leading to a decreased effectiveness of the defense system. Steroid use decreases the glucose tolerance, while there is an increase in insulin resistance. These changes mimic Type II diabetes. These changes seem to be reversible after abstention from the drugs.